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Semi-synthetic cannabinoid (hemp-derived) · Not federally controlled

Delta-8 THC Delta-8, D8, Delta-8-tetrahydrocannabinol

Delta-8 THC is an intoxicating cannabinoid usually made by chemically converting hemp-derived CBD. It has been sold widely in gas stations, vape shops, and online under the 2018 hemp law. It is not FDA-approved, products are often mislabeled or contaminated, and a 2025 federal law ends its hemp protection on November 12, 2026.

Unapproved or unregulated

Draft, awaiting medical review. Updated October 5, 2026.

Onset
Minutes (inhaled); 30 minutes to 2 hours (edibles)
Duration
2 to 4 hours (inhaled); 4 to 8 hours (edibles)
Naloxone reverses it?
No
Dependence risk
Moderate

Delta-8 THC at a glance: schedule, half-life, and class

Chemical name
Delta-8-tetrahydrocannabinol
Drug class
Cannabinoid; CB1 receptor partial agonist
US legal status
Sold as hemp under the 2018 Farm Bill; hemp redefinition takes effect November 12, 2026; banned or regulated in many states
How it is made
Mostly by chemically converting CBD from hemp
Forms
Gummies, vapes, flower sprayed with distillate, tinctures
Potency
Somewhat weaker than delta-9 THC
Drug tests
Usually triggers a positive THC test

What is delta-8 THC?

Delta-8 THC occurs naturally in cannabis only in trace amounts. Products sold in stores are made by chemically converting CBD, sometimes using harsh chemicals, in largely unregulated facilities.[1]

Sellers relied on the 2018 Farm Bill, which legalized hemp with no more than 0.3% delta-9 THC by dry weight. The FDA has not approved delta-8 for any use and has warned companies selling it in food.[1]

Delta-8 THC effects and how long they last

Delta-8 causes a high similar to cannabis: relaxation, euphoria, altered perception, increased appetite, dry mouth, red eyes, and impaired coordination and reaction time. Many people find it somewhat milder than delta-9 THC.[1]

Inhaled effects start within minutes and last 2 to 4 hours. Edibles take 30 minutes to 2 hours and can last 8 hours, which leads people to take more before the first dose has worked.

Delta-8 THC side effects and risks

Unregulated products: testing has found products with far more or less delta-8 than labelled, delta-9 THC above legal limits, and byproducts and residues from chemical conversion.[1]

Children: poison centers have received thousands of reports of delta-8 exposures, many in children who ate gummies or candy-like products; some needed intensive care.[1]

Impairment: driving while impaired by any THC is dangerous and illegal.

Mental health: high doses can cause anxiety, panic, paranoia, and, in some people, psychosis.

Delta-8 THC interactions: what is dangerous to mix with it

Combined withWhat happensGuidance
AlcoholStronger impairment and dizzinessAvoid
Sedatives, opioids, sleep medicinesMore sedationUse caution
Blood thinners and drugs metabolized by CYP enzymesPossible changes in drug levelsAsk a pharmacist

This is not a full list. Combining substances raises the risk of harm, especially when the contents of street drugs are unknown.

Delta-8 THC overdose: signs and what to do

Too much delta-8 can cause extreme sleepiness, confusion, vomiting, a racing heart, panic, and, in children, slowed breathing and coma. Call Poison Help or 911 if a child eats a THC product.[1]

If someone is having a dangerous reaction

  • Call 911 for a seizure, chest pain, a very high temperature, trouble breathing, unresponsiveness, or if the person may harm themselves or others.
  • Move them to a quiet, safe place away from roads, water, heights, and crowds. Stay with them and speak calmly.
  • Do not leave the person alone and do not give them other drugs or alcohol to calm them down.
  • If they become unresponsive, place them on their side and give naloxone in case opioids are involved.

Delta-8 THC withdrawal timeline: symptoms and how long it lasts

Regular, heavy use of THC products can cause cannabis use disorder and withdrawal.[1]

  1. Day 1 to 3Symptoms beginIrritability, anxiety, poor sleep, and decreased appetite.
  2. Days 2 to 6PeakRestlessness, strange dreams, low mood, and cravings.
  3. 1 to 2 weeksResolvesMost symptoms fade; sleep problems can last longer.

Cannabis hyperemesis syndrome, repeated severe vomiting in heavy users, resolves only after stopping THC.

Where can someone get help with delta-8 THC use?

Problem use of delta-8 is treated like other cannabis use disorder.

  • SAMHSA National Helpline: 1-800-662-4357. Free, confidential, 24 hours a day, in English and Spanish. It gives referrals to local treatment and support.[3]
  • FindTreatment.gov: a federal locator for state-licensed treatment programs, searchable by location, payment, and type of care.[4]
  • 988 Suicide and Crisis Lifeline: call or text 988 for a mental health or substance use crisis.
  • Your own clinician: a primary care doctor can screen, treat, and refer, and can discuss medicines that support recovery where they exist.

Common questions about delta-8 THC

Will delta-8 make me fail a drug test?

Very likely. Standard tests detect THC metabolites and do not distinguish delta-8 from delta-9.

Is delta-8 legal?

It has been sold as hemp federally, but many states ban it, and a federal hemp redefinition takes effect on November 12, 2026.

Is delta-8 safer than weed?

Not necessarily. It is somewhat milder, but products are unregulated and often mislabeled or contaminated.

Can you drive after delta-8?

No. It impairs driving like other THC.

What should I do if my child ate a delta-8 gummy?

Call Poison Help at 1-800-222-1222, or 911 if the child is very sleepy, has trouble breathing, or will not wake.

Sources

  1. 5 Things to Know about Delta-8 Tetrahydrocannabinol. US Food and Drug Administration.
  2. New federal restrictions on hemp and hemp-derived products. DLA Piper, November 2025.
  3. National Helpline. Substance Abuse and Mental Health Services Administration.
  4. FindTreatment.gov. Substance Abuse and Mental Health Services Administration.
  5. International drug control conventions. United Nations Office on Drugs and Crime.
  6. Cannabis (Marijuana). National Institute on Drug Abuse.
Read the Delta-8 THC guideKey takeaways, quick facts, and answers to common questions.

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In an emergency in the US, call 911. Poison Help: 1-800-222-1222.