Emergency guide
Someone may be overdosing. Here's what to do.
If the person is unresponsive or breathing slowly, call 911 first. Then pick what they may have taken.
Signs
- Pinpoint pupils
- Will not wake up or respond to a loud voice or a firm rub on the breastbone
- Slow, shallow, or stopped breathing; gurgling or snoring
- Blue or gray lips and fingertips
- Limp body
What to do now
- Call 911.
- Give naloxone: one spray in one nostril. If no response in 2 to 3 minutes, give another dose in the other nostril.
- Give rescue breaths if trained, or place the person in the recovery position.
- Stay until help arrives. Naloxone can wear off before the opioid does.
Signs
- Extreme drowsiness or cannot be woken
- Confusion, slurred speech, poor coordination
- Slow or irregular breathing
- Vomiting while drowsy
What to do now
- Call 911 if the person cannot be woken or is breathing slowly.
- Give naloxone if opioids or street pills could be involved. It is harmless otherwise.
- Place them in the recovery position so they cannot choke on vomit.
- Do not let them sleep it off alone.
Signs
- Chest pain or a racing, irregular heartbeat
- Very hot skin or not sweating in heat
- Severe agitation, paranoia, or confusion
- Seizure, collapse, or signs of stroke
What to do now
- Call 911.
- Move them somewhere cool and calm; cool the skin with water. Do not restrain them.
- If they become unresponsive, give naloxone, since stimulants are often contaminated with fentanyl.
- If they have a seizure, clear the area and time it; do not put anything in their mouth.
Signs
- Extreme panic or terror
- Dangerous behavior or no awareness of danger
- Very high temperature, seizure, or chest pain
- Unresponsive or breathing poorly
What to do now
- Call 911 for any physical danger sign or if they could harm themselves or others.
- Move them to a quiet, safe place and speak calmly. Do not leave them alone.
- Place an unresponsive person in the recovery position.
- Give naloxone if they are unresponsive and opioids could be involved.
Signs
- Cannot be woken
- Slow, noisy, or stopped breathing
- Chest pain, seizure, or very high temperature
- Blue or gray lips
What to do now
- Call 911 and tell them what you see.
- If they are unresponsive or breathing poorly, give naloxone. It is safe even if no opioid was taken.
- Place them in the recovery position.
- Stay with them and keep any packaging or pills for the paramedics.
How to give naloxone nasal spray
- Lay the person on their backTilt the head back and support the neck.
- Insert the nozzle in one nostrilUntil your fingers touch the bottom of the nose.
- Press the plunger firmlyThe full dose sprays at once.
- Wait 2 to 3 minutesIf there is no response, give a second dose in the other nostril.
- Recovery positionTurn them on their side, top knee bent, and stay with them.
Naloxone (Narcan and generics) is sold without a prescription. It only reverses opioids, but it is safe to give when you are not sure.
Staying safer
- Never use alone. If you do, call a never-use-alone hotline or tell someone.
- Test your drugs. Fentanyl, xylazine, and nitazene test strips are legal in most states.
- Start low, go slow. Tolerance drops after a break, and potency varies batch to batch.
- Don't mix. Opioids with sedatives or alcohol cause most overdose deaths. Check a combination.
- Good Samaritan laws in most states protect people who call 911 for an overdose from some drug charges.
Overdose guides by substance
- Alprazolam
- Amphetamine
- Buprenorphine
- Cannabis
- Carisoprodol
- Clonazepam
- Cocaine
- Codeine
- Dexmethylphenidate
- Dextroamphetamine
- Diazepam
- DMT
- Dronabinol
- Esketamine
- Eszopiclone
- Fentanyl
- Gabapentin
- Heroin
- Hydrocodone
- Hydromorphone
- Ketamine
- Kratom
- Lisdexamfetamine
- Lorazepam
- LSD
- MDMA
- Mescaline
- Methadone
- Methamphetamine
- Methylphenidate
- Modafinil
- Morphine
- Nandrolone
- Nitazenes
- Oxycodone
- PCP
- Phenobarbital
- Phentermine
- Pregabalin
- Psilocybin
- Sodium oxybate
- Suvorexant
- Synthetic cannabinoids
- Tapentadol
- Temazepam
- Testosterone
- Tianeptine
- Tramadol
- Xylazine
- Zolpidem