US Controlled Substances Act
Schedule III drugs list (Schedule 3)
Accepted medical use, with moderate to low potential for physical and psychological dependence.
What it means
Accepted medical use, with moderate to low potential for physical and psychological dependence.
Prescribing and refills
Prescription required; up to five refills within six months.
14 Schedule III substances on DoseUses
Buprenorphine
Suboxone, Subutex, Zubsolv
Buprenorphine is a partial opioid agonist and one of the most effective treatments for opioid use disorder.
Read profileButalbital
Fioricet, Fiorinal, Esgic
Butalbital is a barbiturate sedative sold only in combinations, such as Fioricet (with acetaminophen and caffeine) and Fiorinal (with aspirin and caffeine), for tension headaches.
Read profileDronabinol
Marinol, Syndros
Dronabinol (Marinol) is synthetic THC, the main psychoactive compound in cannabis, made as an FDA-approved medicine.
Read profileEsketamine
Spravato
Esketamine (Spravato) is a nasal spray for treatment-resistant depression and for depression with suicidal thoughts.
Read profileKetamine
Ketalar
Ketamine is a dissociative anesthetic used in operating rooms, emergency departments, and battlefield medicine.
Read profileMethandrostenolone
Dianabol, Metandienone, D-bol
Methandrostenolone (Dianabol, 'D-bol') is an oral anabolic steroid developed in the 1950s that was the first widely misused steroid in sport.
Read profileNandrolone
Deca-Durabolin (discontinued)
Nandrolone is an injectable anabolic steroid.
Read profileOxandrolone
Oxandrin, Anavar, Var
Oxandrolone (Anavar, Oxandrin) is an oral anabolic steroid once prescribed for weight loss after surgery, trauma, or infection.
Read profileOxymetholone
Anadrol-50, Drol, A-bombs
Oxymetholone (Anadrol-50) is an oral anabolic steroid approved for anemias caused by the bone marrow not making enough red blood cells.
Read profilePhendimetrazine
Bontril PDM, Bontril SR
Phendimetrazine (Bontril) is a prescription appetite suppressant for short-term use, a few weeks, alongside diet and exercise in people with obesity.
Read profileSodium oxybate
Xyrem, Xywav, Lumryz
Sodium oxybate (Xyrem) is the sodium salt of GHB (gamma-hydroxybutyrate), used to treat cataplexy and daytime sleepiness in narcolepsy.
Read profileStanozolol
Winstrol, Winstrol-V, Winny
Stanozolol (Winstrol) is an anabolic steroid once prescribed in the US for hereditary angioedema.
Read profileTestosterone
AndroGel, Testim, Depo-Testosterone
Testosterone is the main male sex hormone, prescribed to men with confirmed low testosterone caused by a medical condition (hypogonadism).
Read profileTrenbolone
Finaplix, Revalor (veterinary), Tren
Trenbolone ('tren') is a very potent anabolic steroid approved only as a growth implant for cattle.
Read profileSource: DEA Diversion Control Division, Controlled Substance Schedules. Some substances are listed in different schedules depending on the product or formulation; see each profile.